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Actos - Actos is not safe for all patients to day. Patients who have a hypersensitivity to pioglitazone or other components should not take Actos. Additionally, patients with type 1 should not take Actos as it can actually be detrimental, and it should not be used in patients who are suffering from diabetic ketoacidosis. The ability to safely use Actos during pregnancy or while breastfeeding has not yet been established.
Actos is like all other medications on the market in that it can cause unwanted side effects. These side effects may include fractures of the arms, hands and feet. Additionally, it may cause fluid retention, edema, and congestive heart failure. Other patients report headache, respiratory infections, sinusitis, and dental problems.
Glucophage - Glucophage is generally very well tolerated. Those who do experience side effects usually report stomach upset. Even hypoglycemia is very rare when the medication is taken as prescribed. Overdose can be serious as it can cause lactic acidosos. When taken the way it is prescribed, Glucophage will actually help to control blood glucose but will also help lower LDL cholesterol and triglycerides. It is also known to help prevent the heart complications that are often associated with those who have diabetes.
Glucophage has been around since the 1920’s and has proven in that time to be a very valuable medication. While new medications are introduced to the market all the time for the treatment of diabetes, Glucophage continues to be the most popular treatment option for those who have type 2 diabetes. This medication can be used by itself or it can be combined with other medications to achieve optimal blood sugar levels.
Avandia: Avandia is a trade name for a anti-diabetic drug that is classified as a thiazolidinedione. It is what is known as an insulin sensitizer, which basically allows for the receptors in fat cells more responsive to insulin. Avandia is marketed by GlaxoSmithKline and can be used alone or in combination with metformin or flimepiride, both of which are medications used to treat type two. Avandia was a very popular medication for several years, with sales of more than 2.5 billion in 2006, but after reports of adverse reactions were made better known, sales have declined.
Sales declined for Avandia amid reports that it is associated with an increased risk of heart attack. While some studies have found this to be true, others have not. Despite different clinical findings, the drug is involved or the center of many lawsuits against GlaxoSmithKline. More than 13,000 claims have been brought against the company in association with Avandia. Many, including some inside of the FDA, have called for the recall of Avandia, but the FDA has held out and Avandia is still available to patients via prescription.